DEXTROLYTE-60 Solution (Oral)

What is DEXTROLYTE-60

DEXTROLYTE-60 is an oral rehydration solution (ORS) used to restore essential body fluids and electrolytes in patients experiencing dehydration. Each 200ml bottle contains a precise blend of Dextrose, Sodium, and Potassium, making it ideal for managing fluid loss caused by diarrhea, vomiting, excessive sweating, or other gastrointestinal disturbances.

• Dextrose: A simple sugar that serves as a quick source of energy and facilitates the active absorption of sodium and water in the intestines.
• Sodium: An essential electrolyte that regulates fluid balance and supports nerve and muscle function.
• Potassium: Maintains cellular function, supports cardiac rhythm, and helps regulate acid-base balance in the body.

This solution is especially recommended for mild to moderate dehydration in both children and adults. Its formulation complies with WHO and UNICEF guidelines for ORS therapy, making it a safe, effective, and accessible remedy for at-home or clinical use.

How to use DEXTROLYTE-60

Proper administration of DEXTROLYTE-60 ensures optimal rehydration and prevents further complications from fluid loss. It is an oral solution intended to be consumed directly, typically without dilution.

• Adults and older children: Sip the solution slowly in small, frequent amounts. Larger quantities may be consumed if tolerated well.
• Infants and young children: Administer with a spoon or oral syringe in small sips every few minutes. Continue breastfeeding or normal feeding alongside ORS therapy.
• Frequency: After each episode of diarrhea or vomiting, give:
  • Children: 50–100 ml per episode
  • Adults: 200–400 ml per episode
• Do not use as the sole source of nutrition. Continue age-appropriate feeding during treatment.
• Shake well before use and discard any unused solution within 24 hours after opening.

Always consult a physician if symptoms persist for more than 24 hours, if dehydration becomes severe, or if the patient is unable to keep fluids down.

Mode of Action DEXTROLYTE-60

DEXTROLYTE-60 works by replenishing fluids and electrolytes through the oral route, promoting rehydration and correcting electrolyte imbalances. Its mechanism relies on the synergistic action of its components:

• Dextrose: Facilitates the absorption of sodium and water through the sodium-glucose co-transport system in the small intestine. This process enhances fluid uptake and restores plasma volume.
• Sodium: Regulates extracellular fluid volume, helping prevent hyponatremia (low sodium) associated with diarrhea and vomiting.
• Potassium: Corrects losses from vomiting and diarrhea, preventing hypokalemia (low potassium), which could lead to muscle weakness, arrhythmias, or fatigue.

The solution promotes isotonic rehydration, maintaining the body’s fluid balance without causing shifts that might lead to complications like cerebral edema. Its oral delivery bypasses the need for IV therapy, offering a safe, effective, and less invasive alternative for rehydration.

DEXTROLYTE-60 Interactions DEXTROLYTE-60

DEXTROLYTE-60 is generally well-tolerated and has minimal interactions. However, caution is advised in specific clinical contexts where electrolyte or fluid imbalance could be worsened.

• Diuretics: May alter electrolyte balance and potentially increase the risk of hyperkalemia or hyponatremia.
• ACE inhibitors or ARBs: These drugs may raise potassium levels, and when combined with potassium-containing solutions like DEXTROLYTE-60, the risk of hyperkalemia increases.
• Glucocorticoids: May increase sodium retention, leading to elevated blood pressure or fluid overload when taken with sodium-containing fluids.
• Antacids (containing sodium bicarbonate): Risk of metabolic alkalosis when combined with sodium-based fluids.

Always consult with a healthcare professional before initiating treatment if the patient is already taking medications that impact fluid or electrolyte balance. Routine monitoring may be advised in those with renal impairment or cardiac disorders.

Dosage of DEXTROLYTE-60

The dosage of DEXTROLYTE-60 depends on the patient's age, weight, and degree of dehydration. The aim is to replace lost fluids and electrolytes in a stepwise, tolerable manner.

• Adults: 200–400 ml after each diarrheal or vomiting episode. Total daily intake can range from 1–3 liters.
• Children (1–12 years): 50–100 ml after each episode. Monitor for signs of overhydration.
• Infants: 15–30 ml every 15–30 minutes, gradually increasing as tolerated. Continue breastfeeding where applicable.

In severe cases of dehydration, ORS is often used after an initial dose of intravenous fluids. Always adjust the total intake based on clinical response and hydration status. Continue treatment for 24–48 hours or as advised by a physician.

Possible side effects of DEXTROLYTE-60

DEXTROLYTE-60 is generally safe and well-tolerated when used as directed. However, some individuals may experience mild or temporary side effects, especially if used improperly or in those with predisposing health conditions.

• Gastrointestinal discomfort: Mild bloating or nausea may occur due to the sugar content or rapid ingestion.
• Hypernatremia or hyperkalemia: Rare, but possible if taken in large volumes or in patients with impaired kidney function.
• Vomiting: May occur if the solution is consumed too quickly, particularly in young children. Administer in small, frequent sips.
• Allergic reactions: Extremely rare, but may include rash, itching, or swelling. Discontinue use if signs of hypersensitivity appear.

Seek medical attention if serious symptoms like muscle cramps, irregular heartbeat, or confusion occur, as these may signal electrolyte imbalance.

DEXTROLYTE-60 Contraindications DEXTROLYTE-60

While DEXTROLYTE-60 is safe for most users, it should not be administered in specific medical situations where fluid or electrolyte therapy may worsen the patient’s condition.

• Severe dehydration or shock: Requires intravenous rehydration before ORS therapy is considered.
• Renal failure: Impaired ability to excrete potassium and sodium can lead to dangerous electrolyte accumulation.
• Persistent vomiting: Patients unable to retain oral fluids require alternative routes of rehydration.
• Intestinal obstruction or ileus: Oral fluids may worsen discomfort or complications.

Use with caution in patients with heart failure, liver disease, or on fluid restrictions. A physician's assessment is advised before starting therapy in such populations.

Storage of DEXTROLYTE-60

To maintain the quality and effectiveness of DEXTROLYTE-60, it is important to follow proper storage guidelines.

• Store at 15–30°C (59–86°F) in a dry place away from direct sunlight and heat sources.
• Keep tightly closed in the original bottle to avoid contamination.
• Do not freeze. Freezing may cause separation or degradation of ingredients.
• Once opened, the solution should be used within 24 hours and discarded if any sediment, discoloration, or odor is detected.
• Keep out of reach of children to avoid accidental ingestion.

Follow any additional manufacturer instructions printed on the packaging. Do not use past the expiration date indicated on the bottle label.