DESLOR Syrup

What is DESLOR

Overview of FENOFIBRATE: FENOFIBRATE is a medication used primarily to reduce cholesterol levels in individuals with hyperlipidemia. As a fibrate, it works by activating peroxisome proliferator-activated receptor alpha (PPAR-alpha), which plays a crucial role in lipid metabolism. This leads to a significant reduction in triglyceride levels and an increase in high-density lipoprotein (HDL) cholesterol.

Clinical Indications: FENOFIBRATE is often prescribed as part of a comprehensive treatment plan that includes dietary changes and lifestyle modifications. It is particularly beneficial for patients with elevated triglyceride levels or low HDL levels, contributing to improved cardiovascular health and reduced risk of heart disease.

How to use DESLOR

How to Take FENOFIBRATE: For optimal effectiveness, follow these administration guidelines:

• Dosage: The typical starting dose is usually 48 mg or 145 mg once daily, based on the patient’s cholesterol levels and response to treatment.
• Administration: FENOFIBRATE should be taken orally with food to enhance absorption and minimize gastrointestinal discomfort.
• Consistency: Take the medication at the same time each day to maintain stable drug levels in the bloodstream.
• Missed Dose: If you miss a dose, take it as soon as you remember unless it’s almost time for your next dose. Do not double the dose to catch up.

Consult your healthcare provider if you have any questions about your dosing schedule or experience any side effects.

Mode of Action DESLOR

Mechanism of Action of FENOFIBRATE: The therapeutic effects of FENOFIBRATE are primarily due to its action on lipid metabolism:

• PPAR-alpha Activation: FENOFIBRATE binds to and activates PPAR-alpha, which leads to increased fatty acid oxidation and reduced triglyceride synthesis in the liver.
• Enhanced Lipoprotein Clearance: The medication promotes the uptake and clearance of triglyceride-rich lipoproteins from the bloodstream, thus lowering triglyceride levels.
• HDL Cholesterol Increase: FENOFIBRATE is effective in increasing HDL cholesterol levels, which helps in the protective mechanisms against cardiovascular disease.

This multi-faceted approach to lipid regulation makes FENOFIBRATE a valuable agent in managing dyslipidemia.

DESLOR Interactions DESLOR

Drug Interactions with FENOFIBRATE: Being aware of potential interactions is essential for safe use:

• Statins: Concomitant use of FENOFIBRATE with statins may increase the risk of muscle-related side effects, including rhabdomyolysis; careful monitoring is advised.
• Anticoagulants: FENOFIBRATE may enhance the effects of anticoagulants like warfarin, necessitating dosage adjustments and regular INR monitoring.
• Other Antihyperlipidemics: When used with other lipid-lowering agents, the effects may be additive; consult your healthcare provider for monitoring recommendations.
• CYP450 Enzyme Interactions: Medications that affect CYP450 enzyme activity may alter the metabolism of FENOFIBRATE, affecting its efficacy and safety profile.
• Renal Impairment: Caution is advised when prescribing FENOFIBRATE to patients with renal impairment, as dose adjustments may be necessary.

Patients should inform their healthcare provider of all medications they are currently taking to avoid potential interactions.

Dosage of DESLOR

Dosage Recommendations for FENOFIBRATE: Adhering to proper dosing is crucial for safety:

• Standard Dosing: The usual recommended dose is 145 mg once daily for adults, with possible adjustments based on lipid levels and patient response.
• Renal Considerations: For patients with moderate renal impairment, a lower dose may be recommended to prevent accumulation of the medication.
• Monitoring: Regular lipid panel tests should be performed to monitor effectiveness and adjust dosing as necessary.
• Duration of Therapy: FENOFIBRATE is typically prescribed as a long-term treatment, and discontinuation should only occur under medical guidance.
• Patient Adherence: Emphasizing the importance of adherence to prescribed dosing schedules can significantly improve treatment outcomes.

Always follow your healthcare provider’s specific instructions regarding dosage.

Possible side effects of DESLOR

Possible Side Effects of FENOFIBRATE: Patients should be aware of potential side effects:

• Common Reactions: Common side effects may include gastrointestinal disturbances such as nausea, abdominal pain, and diarrhea.
• Rash and Pruritus: Some individuals may experience skin rashes or itching, which could indicate an allergic reaction.
• Liver Function: Regular monitoring of liver function tests is recommended, as FENOFIBRATE may cause elevated liver enzymes in some patients.
• Muscle Pain: Myopathy or muscle pain can occur, especially when combined with statins; patients should report any unexplained muscle weakness.
• Increased Creatinine: Some patients may experience elevated creatinine levels; monitoring kidney function is important during treatment.

Patients should promptly report any severe side effects to their healthcare provider.

DESLOR Contraindications DESLOR

Information not available.

Storage of DESLOR

Storage Conditions for FENOFIBRATE: Proper storage is vital for maintaining the efficacy of FENOFIBRATE:

• Temperature: Store at room temperature, between 20°C and 25°C (68°F to 77°F), away from direct sunlight and moisture.
• Container: Keep FENOFIBRATE in its original packaging, tightly closed, to protect it from light and moisture.
• Child Safety: Ensure the medication is stored out of reach of children to prevent accidental ingestion.
• Expiration Date: Regularly check the expiration date and dispose of expired products safely according to local guidelines.
• Humidity Control: Avoid storing FENOFIBRATE in the bathroom or other humid areas, as moisture can degrade the medication.

Adhering to these storage guidelines will help ensure the medication remains effective throughout its shelf life.