DESLADIN 5 mg Tablet/Film coated

What is DESLADIN 5 mg

Product Overview of DERMOVATE Ointment: DERMOVATE Ointment is a potent topical corticosteroid containing clobetasol propionate as the active ingredient. It is primarily indicated for the treatment of various inflammatory skin conditions that respond to corticosteroids, such as psoriasis, eczema, and dermatitis. DERMOVATE is known for its effectiveness in relieving itching, redness, and inflammation associated with these skin disorders.

Mechanism of Action: Clobetasol propionate works by inhibiting the release of inflammatory mediators from immune cells, thus reducing inflammation and immune responses in the skin. This action leads to decreased redness, swelling, and itching. The ointment formulation provides an occlusive effect that enhances the penetration of the active ingredient into the skin, maximizing its therapeutic benefits.

Uses and Indications: DERMOVATE Ointment is indicated for the treatment of:

• Psoriasis
• Atopic dermatitis
• Contact dermatitis
• Seborrheic dermatitis
• Other corticosteroid-responsive dermatoses

Due to its potency, it should be used under the supervision of a healthcare provider, especially when treating sensitive areas of the body.

How to use DESLADIN 5 mg

How to Use DERMOVATE Ointment: The correct application of DERMOVATE Ointment is crucial to achieve optimal results while minimizing side effects. Patients should adhere to the following instructions:

• Application Instructions: Apply a thin layer of DERMOVATE Ointment to the affected area once or twice daily, as directed by a healthcare provider. Gently massage the ointment into the skin until it is absorbed.
• Avoid Occlusive Dressings: Unless instructed by a healthcare provider, do not cover the treated area with bandages or dressings. Occlusive dressings can increase the absorption of the corticosteroid, leading to potential side effects.
• Duration of Treatment: DERMOVATE should not be used continuously for more than two weeks without reevaluation by a healthcare provider. If improvement is not observed within this timeframe, the treatment plan should be reassessed.
• Children: Caution should be exercised when using DERMOVATE in children, as they are more susceptible to systemic side effects. Use in pediatric patients should be limited to the shortest duration necessary.
• Missed Dose: If a dose is missed, apply it as soon as remembered, unless it is nearly time for the next dose. In that case, skip the missed dose and resume the regular schedule.

Patients should wash their hands after applying the ointment unless treating their hands, to avoid inadvertent exposure to other areas of the body.

Mode of Action DESLADIN 5 mg

Mode of Action of DERMOVATE Ointment: DERMOVATE Ointment, with its active ingredient clobetasol propionate, exhibits its therapeutic effects through several mechanisms:

• Anti-inflammatory Action: Clobetasol inhibits the synthesis and release of pro-inflammatory cytokines, effectively reducing inflammation and associated symptoms such as redness and swelling.
• Immunosuppressive Effects: The ointment suppresses the activity of immune cells in the skin, decreasing the immune response that can exacerbate conditions like eczema and psoriasis.
• Vasoconstriction: DERMOVATE induces vasoconstriction in the skin, resulting in reduced blood flow to inflamed areas and consequently alleviating redness and swelling.
• Enhanced Drug Delivery: The ointment formulation allows for better penetration of clobetasol into the skin, enhancing its efficacy in treating localized skin conditions.

This combination of actions makes DERMOVATE Ointment a powerful option for managing various inflammatory skin disorders.

DESLADIN 5 mg Interactions DESLADIN 5 mg

Interactions with DERMOVATE Ointment: Although topical corticosteroids like DERMOVATE generally have a lower risk of systemic interactions, it is still important for patients to consider potential interactions:

• Other Topical Medications: When using other topical treatments, apply them at different times or as directed by a healthcare provider to prevent interference with absorption.
• Immunosuppressive Medications: Caution is advised when using DERMOVATE alongside systemic immunosuppressants, as it may further compromise the immune response.
• Allergic Reactions: Patients with known hypersensitivity to clobetasol or other corticosteroids should avoid using this ointment to prevent allergic reactions.
• Vaccination Concerns: Use of corticosteroids may diminish the efficacy of vaccines. Patients should inform their healthcare provider if vaccinations are scheduled during treatment.

It is crucial for patients to inform their healthcare provider about all medications they are taking to mitigate potential interactions with DERMOVATE Ointment.

Dosage of DESLADIN 5 mg

Dosage and Administration of DERMOVATE Ointment: The dosage of DERMOVATE Ointment should be tailored to the individual’s condition and response. Below are general dosing guidelines:

• Typical Dosage: Apply a thin layer of DERMOVATE Ointment to the affected area once or twice daily, as directed by a healthcare provider.
• Duration of Use: The maximum recommended duration for continuous use is two weeks. After this period, reevaluation is necessary to determine further treatment.
• Application Technique: Use only a small amount of ointment, gently massaging it into the skin until absorbed. Excessive application may lead to increased risk of side effects.
• Special Populations: In children, the duration of treatment should be minimized, and the area of application should be limited to avoid systemic absorption.
• Missed Dose: If a dose is missed, it should be applied as soon as possible, unless close to the next scheduled dose. In that case, the missed dose should be skipped.

Patients should adhere to the prescribed dosage to ensure safe and effective treatment with DERMOVATE Ointment.

Possible side effects of DESLADIN 5 mg

Side Effects of DERMOVATE Ointment: As with any medication, DERMOVATE Ointment can cause side effects, though not everyone will experience them. Common side effects include:

• Local Reactions: Patients may experience local irritation, burning, stinging, or dryness at the application site. These effects are usually mild and transient.
• Skin Thinning: Prolonged use of potent corticosteroids like clobetasol can lead to skin thinning, striae (stretch marks), and discoloration of the skin.
• Systemic Effects: While rare with topical use, systemic absorption can occur, leading to effects such as adrenal suppression, Cushing’s syndrome, and elevated blood sugar levels.
• Allergic Reactions: Some individuals may develop an allergic reaction characterized by severe itching, rash, or hives. Immediate discontinuation and medical attention are warranted if these occur.
• Secondary Infections: The use of corticosteroids can suppress local immune responses, increasing the risk of secondary skin infections.

Patients should monitor for side effects and report any concerning symptoms to their healthcare provider promptly.

DESLADIN 5 mg Contraindications DESLADIN 5 mg

Information not available.

Storage of DESLADIN 5 mg

Storage Instructions for DERMOVATE Ointment: Proper storage is vital for maintaining the effectiveness of DERMOVATE Ointment. Follow these guidelines:

• Temperature Control: Store the ointment at room temperature, between 20°C and 25°C (68°F to 77°F). Avoid exposure to extreme temperatures, which can compromise the product.
• Keep Sealed: Ensure the container is tightly closed when not in use to prevent contamination and degradation of the ointment.
• Avoid Humidity: Store in a dry location, away from humidity and moisture, as bathrooms are not suitable due to high moisture levels.
• Keep Out of Reach: Store DERMOVATE out of the reach of children and pets to prevent accidental ingestion or misuse.
• Expiration Check: Regularly check the expiration date on the packaging and dispose of any expired products according to local regulations.

By adhering to these storage recommendations, patients can ensure that DERMOVATE Ointment remains effective for its intended use throughout its shelf life.