What is APROVEL 150mg
APROVEL 150mg is a prescription medicine that belongs to the class of drugs known as angiotensin II receptor blockers (ARBs). Its active substance is Irbesartan, used primarily for:
- Treating high blood pressure (essential hypertension)
- Protecting kidney function in patients with type 2 diabetes and hypertension (diabetic nephropathy)
By blocking the action of a natural substance (angiotensin II) that tightens blood vessels, APROVEL allows blood vessels to relax, thereby lowering blood pressure. This helps reduce the risk of strokes, heart attacks, and kidney problems. The 150mg dose is typically used as a starting or maintenance dose depending on your treatment plan.
The medicine comes in film-coated tablets, each box containing 28 tablets packed in two 14-tablet blisters. It's intended for long-term management of blood pressure and should be used consistently under medical supervision.
How to use APROVEL 150mg
To ensure the effectiveness of APROVEL 150mg and minimize risks, follow these usage instructions:
- Take one tablet once a day, with or without food.
- Swallow the tablet whole with water—do not chew or break it.
- Try to take the tablet at the same time each day to maintain even blood levels.
- If a dose is missed, take it as soon as you remember. If it's almost time for the next dose, skip the missed one. Do not double the dose.
- Do not stop the medication abruptly without consulting your doctor, even if you feel better.
For best results, combine APROVEL with a healthy diet, regular exercise, and other medications if prescribed. Monitor your blood pressure regularly and attend follow-up appointments to adjust treatment if needed.
Mode of Action APROVEL 150mg
APROVEL 150mg works by blocking angiotensin II, a hormone that normally causes blood vessels to constrict. The mode of action includes:
- Blocking AT1 receptors: Irbesartan prevents angiotensin II from binding to its receptors on blood vessels, leading to relaxation and dilation.
- Reducing aldosterone secretion: This leads to decreased sodium and water retention, reducing blood volume and pressure.
- Lowering peripheral resistance: Improves blood flow and reduces the workload on the heart.
- Renal protection: Especially in diabetic patients, Irbesartan reduces proteinuria and helps preserve kidney function.
This mechanism makes APROVEL effective in managing blood pressure without significantly affecting heart rate or blood sugar levels, making it suitable for diabetic patients as well.
APROVEL 150mg Interactions APROVEL 150mg
APROVEL may interact with other medications, leading to reduced effectiveness or increased risk of side effects. Notable interactions include:
- Potassium supplements or potassium-sparing diuretics (e.g., spironolactone): Risk of hyperkalemia.
- NSAIDs (e.g., ibuprofen, naproxen): May reduce the blood pressure-lowering effect and harm kidney function.
- Other antihypertensives (e.g., ACE inhibitors, beta-blockers): Can increase the risk of low blood pressure or kidney issues.
- Diuretics: Enhance the antihypertensive effect but may cause dehydration or electrolyte imbalances.
- Lithium: Increased risk of lithium toxicity.
Always inform your doctor about any prescription, over-the-counter, or herbal medications you're taking before starting APROVEL.
Dosage of APROVEL 150mg
The dosage of APROVEL 150mg varies depending on the condition being treated and patient-specific factors such as age, kidney function, and concurrent medications.
- For Hypertension (High Blood Pressure):
- Initial dose: 150 mg once daily
- Maintenance dose: May be increased to 300 mg once daily if needed to achieve optimal blood pressure control
- For Diabetic Nephropathy (Kidney protection in type 2 diabetes):
- Recommended dose: 300 mg once daily
- In Elderly Patients or Those on Diuretics:
- Starting at a lower dose (e.g., 75 mg) may be considered to reduce the risk of hypotension, especially in volume-depleted patients
Always follow your doctor’s exact instructions regarding dosage and do not adjust the dose on your own. Regular monitoring of blood pressure and kidney function is advised during treatment.
Possible side effects of APROVEL 150mg
Like all medications, APROVEL can cause side effects, though not everyone experiences them. Most side effects are mild and temporary, but some may require medical attention.
- Common side effects (may affect up to 1 in 10 people):
- Dizziness or lightheadedness, especially when standing up quickly
- Fatigue or weakness
- Nausea or vomiting
- Headache
- Less common side effects:
- Muscle cramps
- Low blood pressure (hypotension)
- Joint or back pain
- Serious side effects (rare but important):
- High potassium levels in the blood (hyperkalemia), which may cause muscle weakness or irregular heartbeat
- Kidney dysfunction or worsening kidney disease
- Severe allergic reactions (rash, itching, swelling of the face/lips/tongue, or difficulty breathing)
- Fainting or significant drop in blood pressure
If you notice any severe symptoms or allergic reactions, seek immediate medical attention. Always report any unusual or persistent side effects to your healthcare provider.
APROVEL 150mg Contraindications APROVEL 150mg
Do not use APROVEL if any of the following apply:
- Pregnancy: Especially after the first trimester, due to risk of birth defects or fetal death.
- Severe kidney or liver dysfunction, including patients on dialysis.
- Known allergy to Irbesartan or any excipients in the formulation.
- Combination with Aliskiren in patients with diabetes or impaired kidney function.
- Bilateral renal artery stenosis or stenosis in a single functioning kidney.
Always review your medical history and current conditions with your healthcare provider before starting treatment.
Storage of APROVEL 150mg
Proper storage ensures the safety and effectiveness of your medication. Follow these guidelines:
- Store below 30°C (86°F).
- Keep tablets in the original blister pack to protect from light and moisture.
- Do not store in humid places such as bathrooms.
- Keep out of reach of children and pets.
- Do not use after the expiration date printed on the package.
If the tablets appear discolored or damaged, do not use them and consult your pharmacist for replacement.
APROVEL 150mg features an exceptional active ingredient renowned for its potent effects, comprising Irbesartan. This powerful formulation provides a superior solution for addressing diverse health concerns. With 150mg/Tablet concentration and an easily manageable Tablets/Film-coated, it remains a preferred option for countless individuals seeking effective treatment.
Introduction
All you need to know about APROVEL 150mg .
Welcome to Dwaey, specifically on APROVEL 150mg page.
This medicine contains an important and useful components, as it consists of Irbesartan.
APROVEL 150mg is available in the market in concentration 150mg/Tablet and in the form of Tablets/Film-coated.
SANOFI WINTHROP INDUSTRIE is the producer of APROVEL 150mg and it is imported from FRANCE,
The most popular alternatives of APROVEL 150mg are listed downward .
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SANOFI WINTHROP INDUSTRIE
Frequently Asked Questions
APROVEL 150mg should be stored according to the instructions provided by SANOFI WINTHROP INDUSTRIE.
In general, it is recommended to store APROVEL 150mg in a cool, dry place, away from direct sunlight
and out of the reach of children.
The duration of treatment with APROVEL 150mg may vary depending on the condition being treated
and the guidance of your healthcare provider. It is important to follow the prescribed treatment
plan and continue taking APROVEL 150mg for the recommended duration, even if your symptoms improve.
If you have any concerns or questions about the duration of treatment, consult your healthcare provider.
It is important to check with your healthcare provider or read the medication label for specific
instructions regarding alcohol consumption while taking APROVEL 150mg. Some medications, including
APROVEL 150mg, may have interactions with alcohol that can reduce effectiveness, increase side
effects, or pose other risks to your health. It is best to follow the guidance provided by your
healthcare professional.
If you miss a dose of APROVEL 150mg, take it as soon as you remember. However, if it is close
to the time for your next scheduled dose, skip the missed dose and continue with your regular dosing
schedule. Do not take a double dose to make up for a missed one unless advised by your healthcare provider.
No, do not stop taking APROVEL 150mg without consulting your healthcare provider, even if your
symptoms improve. It is important to complete the full course of treatment as prescribed. Stopping
the medication prematurely may lead to a relapse or incomplete resolution of the condition. If you
have concerns about the duration of treatment, consult your healthcare provider for guidance.
It is important to consult your healthcare provider before taking APROVEL 150mg if you are
pregnant or breastfeeding. They will be able to assess the potential risks and benefits based on your
specific situation. Please note that the safety and suitability of APROVEL 150mg during pregnancy
or breastfeeding may depend on the active substance [Active Substance], concentration 150mg/Tablet,
and the specific recommendations of SANOFI WINTHROP INDUSTRIE.
The effects of APROVEL 150mg on your ability to drive or operate machinery can vary depending on
the active substance [Active Substance], concentration 150mg/Tablet, and individual factors.
Some medications may cause drowsiness, dizziness, or other side effects that can impair your judgment
or coordination. It is important to read the medication label or consult your healthcare provider to
understand any potential effects on your ability to perform tasks that require alertness.
The instructions for taking APROVEL 150mg with or without food may vary depending on the medication
and the recommendations of SANOFI WINTHROP INDUSTRIE. Some medications may be more effective when taken with
food to enhance absorption or reduce stomach irritation, while others may need to be taken on an empty
stomach for optimal absorption. Read the medication label or consult your healthcare provider for specific instructions.
The use of APROVEL 150mg in children or elderly individuals may depend on various factors, including
the specific medication, type Tablets/Film-coated, and the recommendations of SANOFI WINTHROP INDUSTRIE. Some
medications may have specific dosing instructions or precautions for these age groups. Consult your
healthcare provider or read the medication label for information regarding the safe and appropriate use
of APROVEL 150mg in children or elderly individuals.
Dwaey
All medical information published on the Dwaey website aims to increase medical awareness and health education among users. However, it is not a substitute for professional medical advice. Always consult with a specialist doctor. We strongly advise against using any information or medicine found on the site without referring to your healthcare provider.
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