DELOHIST 5 mg Tablet/ Film coated

What is DELOHIST 5 mg

DELOHIST 5 mg contains Desloratadine, an antihistamine used to relieve allergy symptoms such as sneezing, runny nose, itchy or watery eyes, and itching of the throat or nose. It is effective in managing both seasonal allergic rhinitis and chronic urticaria (hives), providing 24-hour relief from symptoms without causing drowsiness in most patients.

Desloratadine works by blocking the action of histamine, a substance in the body that causes allergic symptoms. It is a long-acting, non-sedating antihistamine suitable for adults and children over 12 years of age.

DELOHIST is available in tablet form, with each film-coated tablet containing 5 mg of Desloratadine. It is packaged in 30 tablets (10 tablets per blister, 3 blisters per pack) for convenient dosing.

How to use DELOHIST 5 mg

To take DELOHIST 5 mg, follow your healthcare provider’s instructions or the directions on the package. Generally, the recommended dose for adults and children over 12 years is one tablet taken once daily with or without food. Swallow the tablet whole with water, without crushing or chewing it.

• Timing: Take the tablet at the same time each day for consistent relief of symptoms.
• Missed Dose: If you forget to take a dose, take it as soon as you remember unless it’s almost time for your next dose. In that case, skip the missed dose and resume your regular schedule. Do not double the dose to make up for the missed one.

Always adhere to your prescribed dosing regimen and consult your healthcare provider if you have any concerns or need adjustments.

Mode of Action DELOHIST 5 mg

Desloratadine, the active ingredient in DELOHIST 5 mg, is a selective H1-receptor antagonist. It works by blocking the histamine receptors in the body that cause allergic reactions, thereby preventing and relieving symptoms such as sneezing, itching, and runny nose.

Desloratadine is a non-sedating antihistamine, meaning it does not cross the blood-brain barrier to the extent of older antihistamines, reducing the likelihood of drowsiness or sedation. Its long duration of action allows for once-daily dosing, providing continuous relief from allergy symptoms.

• Histamine Blockade: Desloratadine prevents the binding of histamine to its receptors, thus reducing allergic symptoms.
• Non-Sedating: Unlike first-generation antihistamines, Desloratadine is less likely to cause drowsiness, making it ideal for daily use.
• Prolonged Effect: With a long half-life, it provides 24-hour symptom relief, improving the quality of life for allergy sufferers.

DELOHIST 5 mg Interactions DELOHIST 5 mg

DELOHIST 5 mg may interact with other medications, potentially affecting its effectiveness or increasing the risk of side effects. It is important to inform your healthcare provider about all medications you are taking, including over-the-counter drugs and supplements. Some key interactions include:

• Alcohol: Although Desloratadine is non-sedating, combining it with alcohol may enhance the risk of drowsiness in some individuals.
• Ketoconazole and Erythromycin: These medications may increase the concentration of Desloratadine in the blood, potentially leading to an increased risk of side effects.
• CYP3A4 Inhibitors: Drugs that inhibit the enzyme CYP3A4 can affect the metabolism of Desloratadine, altering its efficacy.

Always consult your healthcare provider before starting or stopping any medications while taking DELOHIST 5 mg.

Dosage of DELOHIST 5 mg

The typical recommended dose of DELOHIST 5 mg is:

• Adults and Children Over 12 Years: One tablet (5 mg) taken once daily.
• Special Populations: In individuals with renal or hepatic impairment, your healthcare provider may adjust the dosage.

It is important to follow your healthcare provider’s guidance regarding dosing. Do not exceed the recommended dose without consulting a healthcare professional.

Possible side effects of DELOHIST 5 mg

Like all medications, DELOHIST 5 mg may cause side effects, although not everyone will experience them. Common side effects include:

• Headache
• Dry mouth
• Fatigue
• Sore throat

Serious side effects are rare but may include:

• Allergic reactions such as rash, itching, or swelling
• Difficulty breathing

If you experience severe side effects or signs of an allergic reaction, stop taking DELOHIST and seek medical attention immediately.

DELOHIST 5 mg Contraindications DELOHIST 5 mg

Information not available.

Storage of DELOHIST 5 mg

Store DELOHIST 5 mg tablets at room temperature, away from moisture and heat. Keep the tablets in their original packaging to protect them from light and contamination. Ensure that they are kept out of reach of children and pets.

• Store at 20°C to 25°C (68°F to 77°F).
• Do not use the tablets after the expiration date on the packaging.
• If no longer needed, dispose of the tablets according to local regulations.