Overview

Welcome to Dwaey, specifically on METOPRESS XL 50mg Tablets/Extended Release page.
This medicine contains an important and useful components, as it consists of Metoprolol.
METOPRESS XL 50mg is available in the market in concentration 50mg/Tablet and in the form of Tablets/Extended Release.

PHARMAX PHARMACEUTICALS FZ LLC is the producer of METOPRESS XL 50mg and it is imported from UAE, The most popular alternatives of METOPRESS XL 50mg are listed downward .

Mode Of Action & Indication

Metoprolol selectively inhibits beta1-adrenergic receptors but has little or no effect on beta2-receptors except in high doses. It does not exhibit membrane stabilising or intrinsic sympathomimetic activity.

Indication

• Heart failure
• Migraine
• Acute MI
• Diabetic nephropathy
• Hypertension
• Cardiac arrhythmias
• Angina pectoris

Precaution

Patients w/ myasthenia gravis, well-compensated heart failure, bronchospastic disease, AV conduction disorders, substantial cardiomegaly. May mask signs and symptoms of hyperthyroidism and hypoglycaemia. Patients w/ history of cardiac failure or those w/ minimal cardiac reserve. Patients undergoing major surgery involving general anaesth. Avoid abrupt withdrawal as it may precipitate thyroid storm or MI, and may exacerbate angina and ventricular arrhythmias. Hepatic impairment. Pregnancy and lactation. Patient Counselling May affect ability to drive or operate machinery. Monitoring Parameters Monitor BP, ECG and heart rate. Lactation: Drug is concentrated in breast milk; use with caution (American Academy of Pediatrics states that drug is compatible with nursing)

Side Effects

• 1-10% Dizziness (10%)
• Headache (10%)
• Tiredness (10%)
• Depression (5%)
• Diarrhea (5%)
• .Pruritus (5%)
• Bradycardia (9%)
• Rash (5%)
• Dyspnea (1-3%)
• Cold extremities (1%)
• Constipation (1%)
• Dyspepsia (1%)
• Heart failure (1%)
• Hypotension (1%)
• Nausea (1%)
• Flatulence (1%)
• Heartburn (1%)
• Xerostomia (1%)
• Wheezing (1%)
• Bronchospasm (1%) Frequency Not Defined Decreased exercise tolerance
• Raynaud phenomenon
• Increased triglyceride levels and insulin resistance
• decreased high-density lipoprotein (HDL) levels

Contra indication

2nd or 3rd degree AV block, sick sinus syndrome, hypotension, decompensated heart failure, sinus bradycardia, severe peripheral arterial circulatory disorders, cardiogenic shock, severe asthma and bronchospasm, untreated phaeochromocytoma, Prinzmetal's angina, metabolic acidosis.

Pregnancy and lactation

Pregnancy category: C

Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks