Overview

Welcome to Dwaey, specifically on MALDOCARDIN 5mg Tablets page.
This medicine contains an important and useful components, as it consists of Amlodipine (as besilate).
MALDOCARDIN 5mg is available in the market in concentration 5mg/Tablet and in the form of Tablets.

LIFEPHARMA FZE is the producer of MALDOCARDIN 5mg and it is imported from UAE, The most popular alternatives of MALDOCARDIN 5mg are listed downward .

Mode Of Action & Indication

Amlodipine relaxes peripheral and coronary vascular smooth muscle. It produces coronary vasodilation by inhibiting the entry of Ca ions into the slow channels or select voltage-sensitive channels of the vascular smooth muscle and myocardium during depolarisation. It also increases myocardial oxygen delivery in patients w/ vasospastic angina.

Indication

• Mild to moderate hypertension
• Chronic stable and vasospastic angina
• Raynaud's disease
• Coronary Artery Disease
• HTN
• Stroke prevention

Precaution

Impaired liver or renal function, CHF, sick-sinus syndrome, severe ventricular dysfunction, hypertrophic cardiomyopathy, severe aortic stenosis. Caution when used in patients with idiopathic hypertrophic subaortic stenosis. Elderly, children. Pregnancy, lactation. Use in renal failure: Although Amlodipine is excreted primarily via kidney, mild renal impairment does not appear to have an effect on the plasma concentrations. Severe renal impairment may however require a dosage reduction. Amlodipine is not dialyzable. Use in patients with impaired hepatic function: Amlodipine half-life is prolonged in patient with impaired hepatic function. Amlodipine should therefore be administered at lower (5mg) initial dose in these patients. Use in heart failure: An increased number of pulmonary oedema has been reported. Lactation: Unknown whether drug is excreted in milk; use not recommended

Side Effects

• >10% Edema (1.8-10.8%)
• Pulmonary edema (7-15%) 1-10% Headache (7.3%)
• Fatigue (4.5%)
• Palpitations (0.7-4.5%)
• Dizziness (1.1-3.4%)
• Nausea (2.9%)
• Flushing (0.7-2.6%)
• Abdominal pain (1.6%)
• Somnolence (1.4%)
• Male sexual disorder (1-2%)
• Drowsiness (1%)
• Pruritus (1-2%)
• Skin rash (1-2%)
• Muscle cramps (1-2%)
• Muscle weakness (1-2%) Potentially Fatal: Hypotension
• bradycardia
• conductive system delay and CCF.

Contra indication

Hypersensitivity to Amlodipine or other calcium channel antagonist, Severe hypertension.

Pregnancy and lactation

Pregnancy category: C

Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks