PANADOL COLD AND FLU DAY Tablets (Caplets)

What is PANADOL COLD AND FLU DAY

PANADOL COLD AND FLU DAY is a combination medication formulated to provide effective relief from multiple cold and flu symptoms experienced during the day. It is available in tablet (caplet) form and typically packaged in 24s (3 blister packs of 8 caplets each). The active ingredients include:

• Paracetamol (500 mg): A widely used analgesic (pain reliever) and antipyretic (fever reducer).
• Phenylephrine Hydrochloride (5 mg): A decongestant that helps relieve nasal stuffiness.
• Caffeine (25 mg): A mild central nervous system stimulant that enhances the pain-relieving effects of paracetamol and helps combat fatigue commonly associated with cold and flu.

This daytime formula is designed to keep you alert and active while alleviating symptoms such as:

• Headaches and body aches
• Nasal congestion and sinus pressure
• Fever and chills
• Fatigue and drowsiness (caffeine offsets this)

It is a non-drowsy formula, ideal for use during work or daily activities. PANADOL COLD AND FLU DAY is an over-the-counter remedy suitable for adults and adolescents above a certain age (typically 12+ years), but should be used with caution and according to label instructions or medical guidance.

How to use PANADOL COLD AND FLU DAY

Proper usage is essential to ensure both the safety and efficacy of PANADOL COLD AND FLU DAY. Follow these guidelines:

• Form: Oral caplet
• Route: Swallow whole with a full glass of water
• Food: Can be taken with or without food, depending on individual tolerance

Usage Instructions:

• Adults and children aged 12 years and above: Take 2 caplets every 4–6 hours as needed
• Maximum daily dose: Do not exceed 8 caplets in 24 hours
• Do not use for more than 7 consecutive days without medical advice

Important Tips:

• Do not exceed the recommended dose, especially with other paracetamol-containing products
• Avoid consuming excessive caffeine from other sources (e.g., coffee, tea, energy drinks)
• If symptoms persist for more than 3 days, seek medical evaluation
• Use only during the daytime; use a nighttime cold and flu product if symptoms continue into the evening

Always read the product leaflet before starting, and consult your doctor or pharmacist if you have any underlying conditions or are taking other medications.

Mode of Action PANADOL COLD AND FLU DAY

PANADOL COLD AND FLU DAY provides symptom relief through a multi-ingredient approach. Each component contributes differently:

• Paracetamol:
  • Inhibits prostaglandin synthesis in the brain, reducing pain and fever
  • Acts centrally in the hypothalamus to lower elevated body temperature
• Phenylephrine HCl:
  • A selective α1-adrenergic receptor agonist that causes vasoconstriction in the nasal passages
  • Reduces blood flow to the nasal mucosa, which relieves congestion and sinus pressure
• Caffeine:
  • Stimulates the central nervous system, helping to combat drowsiness and fatigue
  • Enhances the analgesic effects of paracetamol by improving drug absorption and increasing its effectiveness

The synergy between these ingredients allows for effective relief from multiple cold and flu symptoms while helping to maintain daytime energy and alertness.

PANADOL COLD AND FLU DAY Interactions PANADOL COLD AND FLU DAY

Interactions with other drugs can alter the efficacy or safety profile of PANADOL COLD AND FLU DAY. Here are some common and important interactions:

• Other Paracetamol-Containing Products: Increases the risk of liver damage—do not use concurrently
• MAO Inhibitors (e.g., phenelzine, tranylcypromine): Can result in a hypertensive crisis with phenylephrine; avoid use within 14 days
• Tricyclic Antidepressants (e.g., amitriptyline): May enhance cardiovascular side effects of phenylephrine
• Beta-blockers and antihypertensive medications: May reduce their effectiveness due to vasoconstrictive effects of phenylephrine
• Warfarin and other anticoagulants: Regular paracetamol use can increase bleeding risk
• CNS Stimulants (e.g., theophylline): May increase side effects such as jitteriness, insomnia, or palpitations due to caffeine

Alcohol: Should be avoided during treatment due to its hepatotoxic potential when combined with paracetamol and its enhancing effects on caffeine side effects.

Always inform your healthcare provider of all medications and supplements you're taking to minimize risks.

Dosage of PANADOL COLD AND FLU DAY

Correct dosing ensures the medicine works effectively while minimizing the risk of side effects or overdose. Refer to the dosage guide below:

• Age Group: For adults and adolescents aged 12 years and above
• Recommended Dose: 2 caplets every 4–6 hours as needed
• Maximum Dose: No more than 8 caplets in 24 hours

Do not exceed:

• 4 grams of paracetamol in a 24-hour period
• Use for more than 7 days without medical supervision

Special Considerations:

• Liver or kidney impairment: Dose adjustment may be required; consult a physician
• Elderly: May be more sensitive to side effects; use with caution
• Children under 12: Not recommended unless directed by a healthcare provider

If a dose is missed, take the next one as scheduled. Do not double the dose to compensate.

Possible side effects of PANADOL COLD AND FLU DAY

While generally safe for short-term use, PANADOL COLD AND FLU DAY can cause side effects in some individuals. These may range from mild to serious:

• Common:
  • Insomnia
  • Nervousness or restlessness (due to caffeine or phenylephrine)
  • Increased heart rate or palpitations
  • Headache or mild stomach upset
• Less Common:
  • Dizziness
  • Elevated blood pressure
  • Irritability or mood changes
• Rare but Serious:
  • Allergic reactions: rash, itching, swelling, or breathing difficulty
  • Liver damage due to excessive or prolonged use of paracetamol
  • Severe anxiety, tremors, or arrhythmias from caffeine overuse

If you experience symptoms of an allergic reaction or any serious side effect, stop the medication immediately and seek medical attention.

PANADOL COLD AND FLU DAY Contraindications PANADOL COLD AND FLU DAY

There are specific situations where PANADOL COLD AND FLU DAY should not be used due to safety concerns. Avoid this medication if you:

• Are allergic to paracetamol, caffeine, phenylephrine, or any other excipients in the formulation
• Are currently taking or recently stopped MAO inhibitors (within the last 14 days)
• Have severe liver disease or known hepatic insufficiency
• Have uncontrolled hypertension or significant cardiovascular disease
• Have hyperthyroidism, glaucoma, or prostate enlargement (due to phenylephrine effects)
• Are sensitive to stimulants like caffeine or have a history of anxiety disorders

Consult a healthcare provider if you are pregnant, breastfeeding, or have any chronic medical conditions before using this medicine.

Storage of PANADOL COLD AND FLU DAY

Proper storage of medication is crucial for maintaining its effectiveness and safety. Follow these guidelines:

• Temperature: Store below 25°C (77°F)
• Humidity: Keep away from excessive moisture and direct sunlight
• Packaging: Keep the tablets in their original blister packs until use
• Child safety: Store out of reach and sight of children

Disposal: Do not throw unused or expired medication into household waste. Ask your pharmacist how to dispose of medicines you no longer use.