OXIRA RAPID 8mg Tablet/ Film coated

What is OXIRA RAPID 8mg

OXIRA RAPID 8mg is a film-coated tablet containing Lornoxicam, a potent non-steroidal anti-inflammatory drug (NSAID) belonging to the oxicam class. It is designed for rapid relief of pain and inflammation in conditions such as osteoarthritis, rheumatoid arthritis, acute musculoskeletal pain, and postoperative pain.

• Generic Name: Lornoxicam
• Strength: 8 mg per tablet
• Form: Film-coated tablet
• Packaging: 20 tablets (10s Blister x 2)
• Classification: NSAID (non-steroidal anti-inflammatory drug)

The 'RAPID' designation indicates that the formulation is optimized for quicker onset of action, providing prompt symptom relief in acute flare-ups or painful episodes.

How to use OXIRA RAPID 8mg

OXIRA RAPID 8mg should be used strictly under medical supervision. The exact dosage and frequency depend on the severity of the condition and individual patient factors.

• Take the tablet orally with a full glass of water.
• Preferably take it after meals to reduce gastrointestinal irritation.
• Do not crush or chew the tablet—swallow it whole.
• Try to take the medication at the same time each day for consistent therapeutic levels.
• If you miss a dose, take it as soon as you remember. If it’s almost time for the next dose, skip the missed one. Never double up.

Do not consume alcohol while on OXIRA RAPID, as it may increase the risk of gastric side effects. Avoid combining it with other NSAIDs unless prescribed.

Mode of Action OXIRA RAPID 8mg

Lornoxicam exerts its action by inhibiting the cyclooxygenase (COX) enzymes that are involved in the synthesis of prostaglandins, substances responsible for pain, inflammation, and fever.

• Dual COX-1 and COX-2 Inhibition: Blocks both isoforms of cyclooxygenase, reducing prostaglandin production.
• Anti-inflammatory Effect: Inhibits leukocyte migration and inflammatory mediator release.
• Analgesic Action: Decreases the sensitization of nociceptors (pain receptors), offering fast relief.
• Faster Onset: The RAPID version ensures a quicker absorption rate and shorter time to peak plasma levels.

The dual inhibition ensures comprehensive symptom relief, but also necessitates caution in patients with gastrointestinal or renal vulnerabilities.

OXIRA RAPID 8mg Interactions OXIRA RAPID 8mg

OXIRA RAPID 8mg can interact with various medications, potentially altering their effects or increasing the risk of side effects.

• Anticoagulants (e.g., Warfarin): May enhance bleeding risk.
• Antihypertensives (ACE inhibitors, ARBs): May reduce their efficacy and impair renal function.
• Diuretics: May decrease diuretic response and increase renal risk.
• SSRIs and SNRIs: Concurrent use increases the risk of gastrointestinal bleeding.
• Methotrexate: Lornoxicam may increase methotrexate levels and toxicity.
• Cyclosporine: Elevated risk of nephrotoxicity when used together.
• Other NSAIDs or Corticosteroids: Risk of additive gastrointestinal and renal effects.

Always inform your healthcare provider about all medications, supplements, or herbal products you are taking before starting OXIRA RAPID 8mg.

Dosage of OXIRA RAPID 8mg

Dosage should be tailored to the patient's condition and medical history. General guidelines include:

• Adults (Acute Pain): 8 mg to 16 mg daily, usually divided into 1–2 doses.
• Maintenance Therapy: The lowest effective dose should be used to minimize side effects.
• Maximum Daily Dose: Should not exceed 16 mg per day.
• Special Populations: Elderly and patients with mild hepatic or renal impairment may require dose adjustments.

Prolonged use should be reviewed periodically by the prescribing physician to assess efficacy and monitor for potential adverse effects.

Possible side effects of OXIRA RAPID 8mg

OXIRA RAPID 8mg, like other NSAIDs, can cause side effects, especially with long-term use or at higher doses.

• Common Side Effects:
  • Gastrointestinal discomfort (nausea, indigestion, stomach pain)
  • Headache or dizziness
  • Diarrhea or constipation
• Less Common but Serious Side Effects:
  • Gastrointestinal bleeding or ulcers
  • Kidney or liver function abnormalities
  • Elevated blood pressure or edema
• Rare Side Effects:
  • Hematological disorders (e.g., anemia, leukopenia)
  • Allergic reactions such as rash, itching, or anaphylaxis
  • Visual or auditory disturbances

Seek immediate medical attention for signs of serious allergic reactions, black stools, persistent abdominal pain, or difficulty breathing.

OXIRA RAPID 8mg Contraindications OXIRA RAPID 8mg

OXIRA RAPID 8mg should not be used in patients with the following conditions:

• Hypersensitivity: Known allergy to Lornoxicam, other NSAIDs, or any tablet component.
• Active Peptic Ulcer or GI Bleeding: Increased risk of exacerbation.
• Severe Liver or Renal Impairment: May worsen toxicity or lead to accumulation.
• Uncontrolled Heart Failure or Hypertension: Risk of fluid retention and exacerbation.
• Bleeding Disorders: Inhibits platelet function.
• Pregnancy (especially third trimester): May cause premature closure of the ductus arteriosus in the fetus.
• Children: Safety and efficacy not established in pediatric populations.

Always conduct a thorough medical evaluation before initiating therapy with OXIRA RAPID 8mg.

Storage of OXIRA RAPID 8mg

To maintain the efficacy and safety of the product, OXIRA RAPID 8mg should be stored properly.

• Temperature: Store at 20°C to 25°C (68°F to 77°F).
• Humidity: Keep away from moisture. Do not store in bathrooms.
• Light: Protect from direct sunlight and strong artificial light.
• Original Packaging: Keep in blister pack until time of use.
• Keep Away from Children: Store in a secure, childproof location.
• Disposal: Safely dispose of unused or expired tablets through a pharmacy or take-back program. Do not flush.

Improper storage can compromise the tablet’s effectiveness and safety.